This group includes natural and semi-synthetic opiates.
All plain morphine preparations are classified in this group.
Opium, see also A07DA - Antipropulsives.
Plain codeine preparations are classified in R05D - Cough suppressants, excl. combinations with expectorants. Codeine or dihydrocodeine in combination with other analgesics are classified in this group at separate 5th levels by using the 50-series, if the codeine or dihydrocodeine content is 20 mg or more per unit dose. Combinations with a lower content of codeine or dihydrocodeine are classified at the respective 4th levels in N02B or M01A of the other analgesic components (e.g. paracetamol or acetylsalicylic acid).
Combinations with antihistamines and anticholinergic agents are classified here.
Combinations of oxycodone and naloxone are classified in N02AA55.
The DDDs are based on approved dose recommendations.
When establishing DDDs for combination products in the 50-
series, all analgesic components are taken into consideration if the amount of each component is on a therapeutic level.
The DDD, expressed in UD, should normally not exceed the approved dose recommendations for any of the components.
See list of DDDs for combination products, www.whocc.no.
