Preparations, which in addition contain a urine acidifier, such as vitamin C, calcium- or ammonium chloride, are classified at the plain 5th levels.
The parenteral DDD for fosfomycin is based on the use of a single prophylactic dose in connection with surgery, whilst the oral DDD
is based on treatment of uncomplicated lower urinary tract infections given as a single dose of fosfomycin trometamol.
The DDD for spectinomycin is based on the use of a single dose for treatment of uncomplicated gonorrhea.
The DDD for methenamine is based on prophylaxis of urinary tract infections. The DDDs for mandelic acid and nitroxoline are based on the treatment of acute urinary tract infections.
